Randomized trials, guidelines, registries, PROMs and epidemiology.
26 tracked publications · last updated 2026-06-08
Related: AI & Machine Learning · Robotics, Automation & Ergonomics · Navigation, AR-VR, Simulation & 3D Printing · Devices, Implants & Procedures · Biologics & Medical Therapy · Endotypes, Biomarkers & Diagnostics · Skull Base Surgery & Reconstruction
Publications
-
Mupirocin Nasal Irrigation Following Endoscopic Sinus Surgery: A Prospective, Double-Blinded, Placebo-Controlled Trial
Al-Bar MH et al. — Am J Rhinol Allergy (2026-06) · RCT
Randomized double-blind placebo-controlled trial comparing postoperative mupirocin versus saline nasal irrigation after endoscopic sinus surgery for CRS, assessing SNOT-22, endoscopic, and microbiological outcomes.
PubMed · DOI · PMID 42252639 -
Acute exacerbation of chronic rhinosinusitis: clinical and microbiological perspectives from a Saudi tertiary care center
Alfallaj R et al. — Ann Saudi Med (2026-06) · Original
Retrospective cohort characterizing clinical features and middle-meatus bacterial profiles of acute CRS exacerbations across CRS phenotypes.
PubMed · DOI · PMID 42251519 -
Assessing Surgical Extent in Endoscopic Sinus Surgery: A Scoping Review of Scoring Systems
Lein A et al. — Int Forum Allergy Rhinol (2026-06) · Review
Scoping review of 11 instruments for scoring ESS extent/completeness and their links to outcomes and biologic response.
PubMed · DOI · PMID 42223914 -
Olfactory outcomes after primary endoscopic sinus surgery and dupilumab for postoperative recurrence in eosinophilic chronic rhinosinusitis
Saito T et al. — J Laryngol Otol (2026-06) · Original
Study reporting olfactory outcomes after primary ESS followed by dupilumab for postoperative recurrence in eosinophilic CRS.
PubMed · DOI · PMID 42220315 -
Co-occurrence of Bronchiectasis Among Chronic Rhinosinusitis Patients Based on Associated Asthma
Bougher C et al. — Ann Allergy Asthma Immunol (2026-05) · Original
Chart-review study finding bronchiectasis is more common in CRSwNP than CRSsNP and highest in CRSwNP with asthma.
PubMed · DOI · PMID 42225168 -
Smell and the Sinuses: Mechanisms, Evaluation, and Management of Olfactory Dysfunction in Sinonasal Disease
Pierre Z et al. — Ann Allergy Asthma Immunol (2026-05) · Review
Clinical review of mechanisms, evaluation, and management (including biologics) of olfactory dysfunction in inflammatory sinonasal disease.
PubMed · DOI · PMID 42219147 -
Prevalence of Central Compartment Atopic Disease (CCAD): a systematic review and meta-analysis
Falcon RMG et al. — Eur Arch Otorhinolaryngol (2026-05) · Review
Meta-analysis estimating central compartment atopic disease comprises roughly a quarter of CRS cases, with marked regional heterogeneity.
PubMed · DOI · PMID 42215785 -
A Systematic Review and Meta-Analysis of Bacterial Pathogen Prevalence in Acute and Chronic Rhinosinusitis: Implications for Empiric Antibiotic Therapy and Antimicrobial Stewardship
Kim HO et al. — Int J Infect Dis (2026-05) · Review
Meta-analysis showing acute and chronic rhinosinusitis are microbiologically distinct, informing empiric antibiotic and stewardship strategies.
PubMed · DOI · PMID 42214663 -
Tubomanometry and Symptom Outcomes in Eustachian Tube Dysfunction Associated with Chronic Nasal Disease
Anastasiadou S et al. — Audiol Res (2026-05) · Original
Study showing nasal interventions (including FESS for CRSwNP) improve tubomanometry parameters and Eustachian-tube symptom scores.
PubMed · DOI · PMID 42201124 -
Gender Differences in Emotional Burden in Chronic Rhinosinusitis: The Role of Sleep-Related Impairment
Cantone E et al. — J Clin Med (2026-05) · Original
Cross-sectional CRSwNP study showing women report greater emotional distress, with sleep impairment the strongest predictor.
PubMed · DOI · PMID 42194749 -
The Efficacy of Probiotics in Treating Upper Respiratory Tract Infections, Allergic Rhinitis, and Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
Azzi A et al. — Microorganisms (2026-04) · Review
Systematic review/meta-analysis finding strain-specific probiotic benefits for URTI and allergic rhinitis but insufficient evidence in CRS.
PubMed · DOI · PMID 42197372 -
Sinonasal outcomes on nasal acoustics and resonance (SONAR)
Berick N et al. — Rhinology (2026-06) · Original
Mel-frequency cepstral coefficients/spectral analysis detect post-FESS resonance changes missed by conventional acoustic measures.
PubMed · DOI · PMID 41487079 -
One year mepolizumab outcomes in severe, uncontrolled CRSwNP: a real-life study
De Corso E et al. — Rhinology (2025-12) · Real-world cohort
Real-life 1-year mepolizumab outcomes (n=50): polyp size and symptom improvement.
PubMed · DOI · PMID 40631514 -
Predictors, Complications, and Outcomes of CSF Leak Post Endoscopic Endonasal Skull Base Surgery
Vargas-Moreno A et al. — Brain Sci (2025-12) · Cohort
Predictors and outcomes of postoperative CSF leak after EEA.
PubMed · DOI · PMID 41594740 -
ARIA-EAACI Guidelines 2024-2025 Revision: Part I
Sousa-Pinto B et al. — Allergy (2025-12) · Practice Guideline
Part I of the ARIA-EAACI 2024-2025 guideline revision.
PubMed · DOI · PMID 41324154 -
Long-Term Risk of Revision Surgery Following Balloon Sinuplasty Versus Endoscopic Sinus Surgery
Parikh MJ et al. — Ann Otol Rhinol Laryngol (2025-11) · Real-world cohort
TriNetX 5-year retrospective comparison of revision risk and healthcare utilization after balloon sinuplasty vs ESS.
PubMed · DOI · PMID 41190449 -
Novel CRS Subtypes Based on Clinical Features and Response to Treatment
Hamilos DL et al. — J Allergy Clin Immunol Pract (2025-11) · Cohort
MGH cohort (N=942) — clinically derived CRS classifiers that predict treatment response.
PubMed · DOI · PMID 41240050 -
Methodology for the ARIA-EAACI 2024-2025 Guidelines
Bousquet J et al. — Allergy (2025-11) · Methodology
GRADE-based methodology underpinning the ARIA-EAACI 2024-2025 guidelines.
PubMed · DOI · PMID 41268627 -
Recurrence of CRSwNP After Surgery: Risk Factors, Predictive Models, and More
Chen YS et al. — Medicina (Kaunas) (2025-09) · Review
Review of risk factors and predictive (incl. ML) models for CRSwNP recurrence after surgery.
PubMed · DOI · PMID 41011011 -
ESS vs clarithromycin for chronic rhinosinusitis (MACRO)
Philpott C et al. — Lancet (2025-08) · RCT (Phase 4)
Pragmatic multicenter RCT comparing endoscopic sinus surgery vs 3 months clarithromycin alongside intranasal medication in CRS.
PubMed · DOI · PMID 40885584 -
Mepolizumab Effectiveness in Severe Asthma With/Without CRSwNP
Schleich F et al. — Allergy (2025-07) · Real-world pooled
Pooled real-world analysis of mepolizumab in severe asthma with and without CRSwNP.
PubMed · DOI · PMID 40590259 -
Tailoring Evaluations of CRS: Sleep and Memory Through Actigraphy
Moore D et al. — J Pers Med (2025-06) · Original
Actigraphy used to characterize sleep and its memory effects in CRS evaluation.
PubMed · DOI · PMID 40559111 -
Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Sinonasal Malignancy
Khalaf M et al. — Head Neck (2025-05) · Review
Safety and oncologic outcomes of the transcribriform approach for locally advanced sinonasal malignancy.
PubMed · DOI · PMID 40420621 -
Radiation-induced rhinosinusitis in patients with nasopharyngeal carcinoma
Chen SY et al. — Radiother Oncol (2025-05) · Cohort
Characterizes radiation-induced rhinosinusitis in NPC survivors.
PubMed · DOI · PMID 40320176 -
Effects of inflammatory endotypes on disease trajectory in CRSwNP
Dorismond C et al. — J Allergy Clin Immunol (2025-04) · Cohort
Compares time-to-polyp-recurrence between CRSwNP inflammatory endotypes.
PubMed · DOI · PMID 40220908 -
Long-Term Particulate Matter Exposure May Increase Risk of CRSwNP
Lubner RJ et al. — Int Forum Allergy Rhinol (2025-04) · Cohort
Epidemiologic link between long-term PM exposure and CRSwNP risk.
PubMed · DOI · PMID 40257454
Sources indexed via PubMed (NCBI). Each entry links to its PubMed record and DOI.