2026-06-04 — Weekly digest

56 new indexed publications added this week across 6 topic areas.

AI & Machine Learning (8)

  • Impact of real-world confounders on the accuracy of an AI model to support read out of skin prick automated test results — Roux K et al., Rhinology (2026-06) · PubMed · DOI
  • Comment on ‘Evaluating the efficacy and readability of advanced large language models in responding to patients’ frequently asked questions about chronic rhinosinusitis: a comparative analysis’ — Sivri I et al., Eur Arch Otorhinolaryngol (2026-06) · PubMed · DOI
  • AI-Based Quantitative Nasal Cytology for Predicting Eosinophilic Chronic Rhinosinusitis With Nasal Polyps: A Pilot Study — Li J et al., Int Forum Allergy Rhinol (2026-06) · PubMed · DOI
  • Evaluating large language models in chronic rhinosinusitis: methodological constraints and the need for clinically grounded validation — Tahir HN et al., Eur Arch Otorhinolaryngol (2026-06) · PubMed · DOI
  • Assessment system for short-term lower cranial nerve dysfunction following medulla oblongata glioma surgery: risk stratification and optimal surgical strategy — Zhang M et al., J Neurosurg (2026-05) · PubMed · DOI
  • Explainable hybrid CNN-transformer with self-supervised learning for structural analysis of paranasal sinus CT — Ullah N et al., Front Comput Neurosci (2026-05) · PubMed · DOI
  • Automated Classification of Maxillary Sinus Ostium Patency Using a ConvNeXt-Tiny + DeiT Gated MLP-Based Hybrid Deep Learning Model: A Retrospective CBCT Study — Talo F et al., Diagnostics (Basel) (2026-05) · PubMed · DOI
  • Detection of maxillary sinusitis of endodontic origin in cone-beam CT images using deep learning algorithms — Sherif OAS et al., Sci Rep (2026-05) · PubMed · DOI

Robotics, Automation & Ergonomics (1)

  • Transparent augmented-reality head-mounted displays vs medical-grade monitor in laryngologic endoscopy: A comparative FM-100 color discrimination and Fitts’ law pointing study — Dobosz P et al., Comput Methods Programs Biomed (2026-05) · PubMed · DOI

Biologics & Medical Therapy (4)

  • Depemokimab: A twice yearly anti-IL 5 biologic for chronic rhinosinusitis with nasal polyps (CRSwNP) - A narrative review — Park MJ et al., Hum Vaccin Immunother (2026-06) · PubMed · DOI
  • Real-world impact of mepolizumab on symptom control and health utility in severe chronic rhinosinusitis with nasal polyps: the RINOSUR 2.0 multicenter cohort study — Corrales-Millan R et al., Eur Arch Otorhinolaryngol (2026-06) · PubMed · DOI
  • Mepolizumab improves outcomes in patients with CRSwNP with one or more prior nasal polyp surgeries — Han JK et al., Rhinology (2026-05) · PubMed · DOI
  • Rebuilding the Mucociliary Apparatus in ECRS: TSLP/IL-33 Signaling Synergy and the Residual Molecular Scar Following IL-4/13 Blockade — Fujita R et al., Cells (2026-05) · PubMed · DOI

Endotypes, Biomarkers & Diagnostics (16)

  • Eosinophils in the immunologic spectrum of Eosinophilic Granulomatosis with Polyangiitis: From Fundamental Pathobiology to Emerging Therapeutic Strategies and Future Perspectives — Hasegawa R et al., Intern Med (2026-06) · PubMed · DOI
  • Chronic rhinosinusitis with nasal polyps (CRSwNP) through an epigenetic lens: Plasmacytoma variant translocation 1 (PVT1) as a potential biomarker and therapeutic target — Gangwar RS, Ann Allergy Asthma Immunol (2026-06) · PubMed · DOI
  • Nasal nitric oxide is inversely associated with radiologic severity and eosinophilic inflammation in chronic rhinosinusitis — Kiyohara K et al., Auris Nasus Larynx (2026-06) · PubMed · DOI
  • Improvement of Mixed Inflammatory Environment in Nasal Secretions of Diffuse Type 2 Chronic Rhinosinusitis With Nasal Polyps Under Dupilumab — Ryser FS et al., Clin Transl Allergy (2026-06) · PubMed · DOI
  • Potential Clinical Impact of Sinonasal Biofilms in CRS: A Structured Evidence Synthesis — Holley HA et al., Int Forum Allergy Rhinol (2026-06) · PubMed · DOI
  • From Tregs to tissue remodelling: FOXP3 and IL-35 in the inflammatory landscape of nasal polyps — Gokulakannan G et al., Inflamm Res (2026-06) · PubMed · DOI
  • Predictive value of TXNIP/NLRP3 signaling pathway expression in nasal polyps for postoperative recurrence of chronic sinusitis with nasal polyps — Lin X et al., Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2026-06) · PubMed · DOI
  • Disease-specific differences in particulate matter handling drive pathogenic responses in human derived nasal epithelial cells — Li Y et al., bioRxiv (2026-05) · PubMed · DOI
  • Fractional exhaled nitric oxide and nasal nitric oxide as biomarkers in chronic rhinosinusitis — Solinas A et al., Curr Opin Allergy Clin Immunol (2026-05) · PubMed · DOI
  • Ca2+ signaling in chronic rhinosinusitis with nasal polyps: Deciphering mechanistic insights and future therapeutic targets — Kalaji Z et al., J Adv Res (2026-05) · PubMed · DOI
  • Epithelial SERPINB2 Overexpression Contributes to Impaired Fibrinolysis in Chronic Rhinosinusitis With Nasal Polyps via tPA Downregulation — Zhu Y et al., Front Biosci (Landmark Ed) (2026-05) · PubMed · DOI
  • CBC-Derived Biomarkers Associated With Recurrence After Sinus Surgery in Chronic Rhinosinusitis — Kirtsreesakul V et al., Laryngoscope (2026-05) · PubMed · DOI
  • Serum metabolic biomarkers associated with self-reported chronic rhinosinusitis: a population-based cross-sectional study from the KNHANES — Chen H et al., Braz J Otorhinolaryngol (2026-05) · PubMed · DOI
  • Distinct Histopathological and Transcriptomic Signatures of Central Compartment Atopic Disease — Han L et al., Int Arch Allergy Immunol (2026-05) · PubMed · DOI
  • Association Between Fungi and Postoperative Recurrence in Eosinophilic Chronic Rhinosinusitis — Adachi N et al., Am J Respir Crit Care Med (2026-05) · PubMed · DOI
  • Pathway-Specific Effects of Oral Corticosteroids on Eosinophilic Inflammation and Tissue Remodeling in Chronic Rhinosinusitis with Nasal Polyps — Radajewski K et al., Int J Mol Sci (2026-05) · PubMed · DOI

Skull Base Surgery & Reconstruction (18)

  • Safety and Efficacy of Expedited Discharge Protocols After Endoscopic Endonasal Pituitary Surgery: A Single-Center Cohort Study — de Souza DN et al., Neurosurgery (2026-06) · PubMed · DOI
  • Use of the Nasoseptal Flap for Inner Lining Reconstruction: Expanding Beyond Skull Base Repair — Nour S et al., Plast Reconstr Surg Glob Open (2026-06) · PubMed · DOI
  • Resection of Vestibular Schwannoma in a Highly Pneumatized Temporal Bone with Fat Graft-Assisted CSF Leak Prevention: A Case-Based Technical Video Report — Huang C et al., World Neurosurg (2026-06) · PubMed · DOI
  • Multimodal Management and Predictors of CSF Leak Following Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenomas — Soliman MA et al., World Neurosurg (2026-06) · PubMed · DOI
  • Endoscopic endonasal surgery for nasopharyngeal angiofibroma — Fernandez Long F et al., Arch Argent Pediatr (2026-06) · PubMed · DOI
  • Delayed Internal Carotid Artery Pseudoaneurysm Following Endoscopic Endonasal Approach for Anterior Clinoid Process Mucocele Treated with Flow Diversion and Adjunctive Coil Embolization: A Case Report — Kim YJ et al., J Korean Neurosurg Soc (2026-06) · PubMed · DOI
  • Endoscopic endonasal management of sellar/suprasellar arachnoid cysts: tailored surgical strategies and systematic review — Uzuner A et al., J Clin Neurosci (2026-06) · PubMed · DOI
  • Effect of pituitary stalk preservation in endoscopic endonasal surgery for suprasellar craniopharyngiomas: a tertiary center experience — Emengen A et al., Neurosurg Focus (2026-06) · PubMed · DOI
  • Endoscopic endonasal approach for recurrent craniopharyngioma in adults — Zoli M et al., Neurosurg Focus (2026-06) · PubMed · DOI
  • Delayed-onset cavernous sinus dural arteriovenous fistula after nasoseptal flap reconstruction: illustrative case — Ishikura T et al., J Neurosurg Case Lessons (2026-06) · PubMed · DOI
  • Predictors of hospital length of stay, discharge disposition, and readmission after craniopharyngioma surgery: a multicenter study from the RAPID database — Tenhoeve SA et al., Neurosurg Focus (2026-06) · PubMed · DOI
  • Endoscopic endonasal gross-total resection of pediatric craniopharyngioma invading the hypothalamus: rethinking the role of surgery — Yang AB et al., Neurosurg Focus (2026-06) · PubMed · DOI
  • Clinical outcomes and delayed proton therapy following endoscopic endonasal resection of large and giant pediatric craniopharyngiomas — Levy DM et al., Neurosurg Focus (2026-06) · PubMed · DOI
  • Endoscopic Management of Sinonasal Ossifying Fibroma: Clinical Experience From a Single Institution — Lee HS et al., J Craniofac Surg (2026-06) · PubMed · DOI
  • The clinical features and treatment outcomes of primary inflammatory lesions in infratemporal fossa: a report of 10 cases — Lai Y et al., Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2026-06) · PubMed · DOI
  • Clinical Outcomes and Failure Patterns After Postoperative IMRT for Olfactory Neuroblastoma: Late Cervical Nodal Relapse — Nishida A et al., Anticancer Res (2026-06) · PubMed · DOI
  • Transoral endoscopic approach to skull base lesions: A 10-year experience at a single tertiary center — Nasirmohtaram S et al., Neurosurg Rev (2026-05) · PubMed · DOI
  • Pituitary adenomas associated with hydrocephalus: clinical characteristics, risk stratification, and clinical management — Zhou W et al., J Neurooncol (2026-05) · PubMed · DOI

Outcomes, Guidelines & Epidemiology (9)

  • Assessing Surgical Extent in Endoscopic Sinus Surgery: A Scoping Review of Scoring Systems — Lein A et al., Int Forum Allergy Rhinol (2026-06) · PubMed · DOI
  • Olfactory outcomes after primary endoscopic sinus surgery and dupilumab for postoperative recurrence in eosinophilic chronic rhinosinusitis — Saito T et al., J Laryngol Otol (2026-06) · PubMed · DOI
  • Co-occurrence of Bronchiectasis Among Chronic Rhinosinusitis Patients Based on Associated Asthma — Bougher C et al., Ann Allergy Asthma Immunol (2026-05) · PubMed · DOI
  • Smell and the Sinuses: Mechanisms, Evaluation, and Management of Olfactory Dysfunction in Sinonasal Disease — Pierre Z et al., Ann Allergy Asthma Immunol (2026-05) · PubMed · DOI
  • Prevalence of Central Compartment Atopic Disease (CCAD): a systematic review and meta-analysis — Falcon RMG et al., Eur Arch Otorhinolaryngol (2026-05) · PubMed · DOI
  • A Systematic Review and Meta-Analysis of Bacterial Pathogen Prevalence in Acute and Chronic Rhinosinusitis: Implications for Empiric Antibiotic Therapy and Antimicrobial Stewardship — Kim HO et al., Int J Infect Dis (2026-05) · PubMed · DOI
  • Tubomanometry and Symptom Outcomes in Eustachian Tube Dysfunction Associated with Chronic Nasal Disease — Anastasiadou S et al., Audiol Res (2026-05) · PubMed · DOI
  • Gender Differences in Emotional Burden in Chronic Rhinosinusitis: The Role of Sleep-Related Impairment — Cantone E et al., J Clin Med (2026-05) · PubMed · DOI
  • The Efficacy of Probiotics in Treating Upper Respiratory Tract Infections, Allergic Rhinitis, and Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis — Azzi A et al., Microorganisms (2026-04) · PubMed · DOI

Indexed via PubMed (NCBI). Every entry links to its PubMed record and DOI.